Release of ISOgray Proton Treatment Planning System with Pencil Beam Scanning Technique

Cachan | Thursday, July 27^th, 2017

DOSIsoft SA, leading software solution provider, specialized in Radiation Oncology and Molecular Imaging, announces the official release, with CE marking, of ISOgray Treatment Planning System (TPS) release 4.3 for proton therapy with active scanning beams (Pencil Beam Scanning). This significant milestone has been achieved through close collaboration with Institut Curie – Protontherapy Center of Orsay (ICPO) in France.

ISOgray-Proton: accurate, fast and powerful treatment of patient by proton therapy

Due to high energy of proton beams and specific dose deposit phenomena, proton therapy planning requires particular dose computation accuracy for dealing with uncertainties, according to the dose delivery technique.

ISOgray-Proton software is now available for modeling and computing dose distributions with Double Scattering beams and Pencil Beam Scanning (PBS) technologies of IBA Proton treatment machines.

The latest development offers new features such as: Single Field Uniform Dose (SFUD) optimization to deliver a uniform dose per field in a target volume and Exacor module used to carry out PBS verification plans as well as to compare the results obtained with measurements from various detectors (eg IBA-MatriXX).

Robust optimization algorithms based on Pencil Beam Kernel dose calculation model, are available with user-friendly interface to offer highly conformal treatments.

ISOgray-Proton: a fruitful collaboration between Institut Curie and DOSIsoft

In the context of a modernization project of its center since 2010, Institut Curie – Protontherapy Center of Orsay (ICPO) near Paris, France – the 2nd European center and 4th center in the world – and DOSIsoft have been collaborating actively since then for new algorithm implementation and joint research activities.

“As the first center in France to implement ISOgray-Proton, ICPO confirms the promising results from the partnership. This proton therapy planning technology offers new modalities to facilitate the treatment of tumors situated near important organs and structures like cranial base tumors.” comments Ludovic De Marzi, medical Physicist at ICPO. “This CE marking is a major step in the collaboration developed over the past 15 years between the Institut Curie and DOSIsoft.” adds Amaury Martin, Director of the Technology Transfer and Industrial Partnerships Office at the Institut Curie.

“As both historic and innovative actor on the TPS market, we are proud of this achievement, obtained through this active partnership and collaboration with the Institut Curie. It demonstrates our commitment to advanced proton therapy treatments and more generally to advanced software products for improving cancer treatments” said Marc Uszynski, CEO of DOSIsoft.

About ISOgray

Treatment Planning System includes proton therapy module. It is a fully independent solution and can be perfectly integrated within the complete TPS solution for photons, electrons and brachytherapy. This software is based on a choice of optimal methods of dose computation for proton beams to obtain speed and accuracy (Ray tracing , Pencil beam).

About Institut Curie – Protontherapy Center of Orsay

Reference center in the treatment of certain eye, cranial and pediatric tumors, also treat patients with chordomas, chondrosarcomas, rare bone tumors, meningiomas and related tumors. Protontherapy forms part of the radiotherapy arsenal offered by the Radiotherapy Oncology department of Institut Curie, the best-equipped center in France. www.curie.fr

About DOSIsoft

Founded in 2002, DOSIsoft develops cutting-edge software solutions for Radiation Oncology and Nuclear Medicine. 15 years of innovation and R&D investments have led to world leading software solutions used successfully in over 160 hospital centers in 18 countries around the world. Spin-off between Gustave Roussy and Institut Curie, DOSIsoft constantly innovates in partnership with the major cancer institutes and research centers in the world. www.dosisoft.com